A team of scientists from the University of Bristol, led by Adam Perryman, has developed a technology for "soldering" individual cells together. To do this, they had to learn how to modify the structure of their membranes. The result is a new kind of extracellular matrix, with a special structure and protection.
They took human mesenchymal stem cells and treated them with the enzyme thrombin, a key component of the wound healing process. After being placed in a solution with fibrinogen, the cells began to actively secrete the hydrogel. With its help, cell membranes were reliably attached to each other, resulting in the formation of a complex but stable three-dimensional structure.
These stem cells are easily transformed into connective tissue, so the fused matrix can be used as a "patch" to quickly repair damage in the human body. Or use the particles of the solution as an analogue of surgical glue. It is very important here that the created matrix protects cells during transplantation and allows them to calmly develop in a new place, without the risk of being destroyed in a foreign environment.