Researchers at the Swedish Royal Institute of Technology have developed a substance that will allow the creation of biocompatible "patches" in the place of damaged bone tissue. And thus eliminate them without installing metal pins or plates. They took as a basis a polymer resin, which is already used for filling teeth.
The principle of the bone patch is identical to that of the teeth. First, an acidic ointment is applied to the damaged area to etch the surface and expose collagen fibers. Then a layer of polymer resin is put there, which contains microparticles - they adhere to collagen fibers and create a stable bond. It remains to illuminate the patch to start the thiol-alkene curing reaction of the substance.
Swedish scientists have developed a special version of a polymer resin, which, in addition to strength, provides the required level of flexibility of the bone substance. It is 55% more effective than simple resin, according to the results of experiments on the bones of rats. The technology is now being prepared for clinical trials, and if successful, Biomedical Bonding AB will develop a commercial version of the drug.
The technique has colossal prospects associated with the fact that previously the very idea of bonding bones remained the lot of science fiction. There were no suitable materials for this. Now, in theory, it will be possible to heal an arbitrarily complex fracture - it will be about the same as gluing a broken vase. Difficult, risky, but possible.