At the World Organ-on-Chip Congress in Boston, a £ 26 million Man in a Chip was presented. Using real tissues, scientists reproduced the work of seven organs and combined them into a microsystem that mimics real human physiology.
Previous similar developments were limited to chips "liver", "lungs" and part of the "intestinal tract". This time, several organ-chips were combined into a microsystem, similar to the human body. The creators of the chip are specialists from the medical company CN Bio Innovations.
This technology, in their opinion, will help to test potentially dangerous drugs and their effect on the human body, eliminating the need to involve volunteers and experimental animals in testing.
The chips are made of flexible polymer with many microscopic channels that mimic the circulatory system. Porous, flexible membranes are placed inside the channels and cells of the "human", grown or implanted from material collected during surgery.
"Blood" is a nutrient-rich liquid that can carry oxygen. So in the case of the "lungs" blood vessels carry and pass oxygen through the mucous membrane. The entire structure can be contracted just like real lungs.