Scientists are gradually solving the problem of the lack of donor tissue. A big step forward is the recently developed 3D printer for the reconstruction of human muscle and tissue. As an experiment, after "printing" the organs were implanted under the skin of the animals, where they were overgrown with the circulatory system and the necessary tissues.
The know-how belongs to the scientists of the Wake Forest Medical Center. To achieve success, they mastered the bioprinting method for several years as a means of replacing damaged tissues. As a result, special bio-ink and a printer were created for this.
Printer ink is a water-based biogel containing stem cells combined with biodegradable polymers arranged in a temporary lattice structure. The water-based gel has been redesigned to promote cell growth.
All this was combined with microchannels, through which nutrients and oxygen from the body are delivered to ensure the vital activity of the "imprinted" organs, where the system of blood vessels must then form.
As an experiment, a miniature ear with a size of 1.5 x 3.8 cm was printed, which was then implanted under the skin of a laboratory mouse, where after 1-2 months signs of vascularization appeared in the ear tissue - the formation of the vascular system. Then similar experiments were carried out with printed muscle tissue, a fragment of the jaw, implanted under the skin of rats. There, positive results appeared after 2 weeks.
One of the research leaders, Anthony Atala, does not hide his optimism:
"Our new organ and tissue printer is an important step forward in our commitment to making tissue replacement affordable to those in need."